Introduction and objective: Radiologists frequently encounter requests from healthcare professionals to evaluate the placement of central venous catheters(CVCs)and to identify potential complications that may arise during their insertion.The confirmation of the CVC tip's precise location is typically performed through the acquisition of a bedside chest radiograph following directly catheter placement, prior to the commencement of any medical interventions involving the catheter.Radiological control of the position of the central catheter begins at the stage of performing the procedure. Ultrasound examination is not only used to locate the vessel, but also allows for the assessment of its anatomy, patency and adjacent structures.CVCs are commonly inserted in critically ill patients to facilitate the monitoring of hemodynamic parameters and to administer of parenteral nutrition or medications.These catheters are typically introduced into either the internal jugular or subclavian vein. What's already known about this topic?: The placement of a central venous catheter is a routine procedure in hospital settings. Such a collaborative approach between radiologist and healthcare professionals is pivotal in optimizing patient’s care and treatment outcomes.The first-line modality to ensure accurate location and identifying potential complications is an X-ray imaging. Abstract: Central line insertion is a procedure involving the cannulation of a wide-diameter vein. This procedure is performed in hospitalized patients requiring long-term intravenous administration of drugs, potent medications - including catecholamines, high osmolarity substances and vascular irritants, such as parenteral nutrition solutions or chemotherapeutics.Central venous access allows monitoring of hemodynamic parameters and can be used as an introducer for the endocavitary electrode, enabling electrical stimulation of the myocardium.Inserting a central line may be associated with many complications, such as: pneumothorax, bleeding, too shallow, too deep or incorrect location of the catheter.Radiological assessment of the location of the catheter positioned in superior vena cava before it is used for drug delivery is the basis for safe use of central vascular access.