Pheochromocytoma is a rare, mostly benign catecholamine-producing tumor that arises from chromaffin cells of the adrenal medulla. In most cases the symptoms are not specific for this disease. Multidrug-resistant hypertension could be one of them. In this case report, we present a patient who had been treated for years because of hypertension without any response to treatment. During diagnostic process pheochromocytoma have been found and proper treatment provided. It should be noted that not only the clinical symptoms, but also the planning of an appropriate diagnostic in close cooperation with the radiologists, is very important during the whole diagnostic.