Introduction and objective: Metabolic syndrome - according to various definitions - is not a disease state, but a set of certain disorders of varying severity, usually metabolic disorders. The term metabolic syndrome (MS) defines the coexistence of interrelated risk factors of metabolic origin, conducive to the development of atherosclerotic cardiovascular diseases and type 2 diabetes. The aim of the study was to assess the level of knowledge of bus drivers employed in MZA about the metabolic syndrome and its relationship with their profession. Material and methods: The study was conducted using the diagnostic survey method with the use of a proprietary questionnaire on a group of 201 employees of the bus depot of the branch of the Municipal Bus Company in Warsaw. Results: The conducted research shows that bus drivers have knowledge about the metabolic syndrome and the factors causing it. Respondents do not suffer from hypertension, and the vast majority do not suffer from diabetes, declare that they do not have elevated cholesterol or do not know anything about it. Every fourth respondent has an abnormal body weight, being aware that the work of a driver predisposes to obesity. Most of the respondents do not show pro-health activities. Bus drivers know that shift work predisposes to obesity, high blood pressure and diabetes. The age of the subjects and the level of education did not significantly affect the level of knowledge of the subjects about the metabolic syndrome. Conclusions: Respondents definitely associate the work of a driver with the occurrence of diseases related to the metabolic syndrome, i.e. obesity, hypertension and diabetes; Most of the respondents answered positively to the question about the relationship between obesity and shift work. However, it is necessary to intensify activities motivating compliance with the recommendations concerning the prevention and promotion of employees' health, both in and outside the working environment.