Introduction and objective: The salivary glands can be categorized into major and minor. This article focuses on the main salivary glands, namely the three paired salivary glands, including the parotid, submandibular and sublingual. The most common salivary gland lesions encountered by radiologists are inflammation (sialadenitis), duct stones (sialolithiasis) and ductal dilatation (sialectasis). The aim of this paper is to briefly summarise the diagnostic imaging options for salivary glands, ensuring that patient management is both appropriate and systematic. What's already known about this topic?: While the issue is well-recognized in selected specialties, it is crucial to disseminate this knowledge across all medical disciplines and encourage interdisciplinary treatment approaches. Abstract: Benign tumors most often affect the parotid gland, and 50% of them affect the submandibular gland. Following the principle that the smaller the gland, the greater the risk of malignancy - cancer lesions in the sublingual salivary glands and small salivary glands are usually malignant. It is essential to note that there are thousands of small salivary glands in the mucous membrane of the mouth and throat. The diagnostic assessment of nodular lesions of the salivary glands is based on radiological and clinical criteria, and the best and most accessible way to make the diagnosis is FNAC or CNB examination supported by ultrasound planning. In addition to the well-established role of ultrasound, in questionable cases it may be necessary to perform cross-sectional imaging tests to obtain a more accurate diagnosis in terms of location, size, topography of the lesion and potential vascular or nerve infiltration, which will enable the selection of the most appropriate surgical treatment.